Ultrasonic generator and transducer principle of ultrasonic cell pulverizer

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Shanghai Xinzhuang Instrument Co., Ltd. develops the ultrasonic cell crusher of Xinzhuang (LNB) brand, which is energy-saving and environmentally friendly and domestically leading. Professional manufacturing is more secure and affordable. The company has professional temperature control technicians and advanced production equipment; perfect production process; to ensure product quality; to achieve safe production. Strive for beautiful, practical, stable and cost-effective products, and strive to save more experimental space for our customers. We will continue to provide you with safe, stable and high-performance experimental equipment to make your experiment process easier.
Basic principle of ultrasonic cell pulverizer Ultrasonic cell pulverizer uses the dispersion effect of ultrasonic waves in liquid to cause cavitation of liquid, thereby breaking solid particles or cell tissue in liquid. The ultrasonic cell pulverizer consists of two parts: an ultrasonic generator and a transducer. The ultrasonic generator converts the utility power into an 18-21 KHz alternating power supply transducer. The zirconium titanate piezoelectric vibrator is the heart of the transducer. It is elastically deformed with an alternating voltage at a frequency of 18-21 kHz, and the transducer is subjected to longitudinal mechanical vibration. The vibration wave generates a cavitation effect by the titanium alloy horn immersed in the biological solution, and the biological particles in the excitation medium vibrate violently.
Ultrasonic Cell Crusher Brief Description Ultrasonic is a kind of elastic mechanical wave in a medium. It is a form of wave, so it can be used to detect physiological and pathological information of the human body, and to diagnose ultrasound. At the same time, it is a form of energy. When a certain dose of ultrasound is transmitted in the living body, the interaction between the two can cause the function and structure of the organism to change, that is, the ultrasonic biological effect. The effects of ultrasound on cells are mainly thermal effects, cavitation effects and mechanical effects. The thermal effect is that when the ultrasound propagates through the medium, the friction hinders the molecular vibration caused by the ultrasound, converting part of the energy into local high heat (42-43 ° C), because the critical lethal temperature of normal tissue is 45.7 ° C, and the tumor tissue ratio Normal tissue sensitivity is high, so at this temperature, the metabolism of tumor cells is impaired, DNA, RNA, and protein synthesis are affected, thereby killing cancer cells and normal tissues are not affected. The cavitation effect is that under the irradiation of ultrasound, vacuoles are formed in the living body, and mechanical shear pressure and turbulence are generated along with the vibration of the vacuole and its violent explosion, which causes the tumor to hemorrhage and the tissue to collapse and cause necrosis. In addition, when the cavitation bubble bursts, it generates instantaneous high temperature (about 5000 ° C) and high pressure (up to 500 × 104 Pa), which can thermally dissociate the water vapor to produce .OH radicals and .H atoms, which are composed of .OH radicals and .H. Atomic induced redox reactions can lead to polymer degradation, enzyme inactivation, lipid peroxidation, and cell killing. The mechanical effect is the primary effect of ultrasound. During the propagation process, the medium particles alternately compress and stretch to form a pressure change, causing damage to the cell structure. The intensity of killing is closely related to the frequency and intensity of ultrasound.
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