The Chinese manual for the EMD Millipore inhibitor kit is distributed for free! Apply quickly!
Merck Millipore's latest Chinese version of the inhibitor kit manual has come out, including the latest inhibitor small molecule library and kit product collection and usage tips, a necessary research tool manual for signaling pathway researchers! Brand, trustworthy!
To obtain the Inhibitor Kit Manual, click here >>
The content of the manual is as follows:
abstract:
Why use small molecules in biological process research?
Chemical biology has been successfully used to explore various biological processes in the methods of "gain of function" and "loss of function". For example, in chemical genetics, small organic molecules or peptides are used to activate or inhibit specific proteins / enzymes in specific cell conduction pathways. This helps researchers analyze the cell phenotype when specific cellular proteins are induced or suppressed.
Compared with other research methods (such as plasmid DNA overexpression or gene knockout), chemical genetics is simpler in operation technology, which is easy to implement on cultured cells, and requires less experimental conditions and less operation time. Compared with the RNAi method, the advantage of the small molecule method is that it has a rapid onset of action, and it can often be removed by simple rinsing to further determine its function. Most small molecules are effective very quickly and make them ideal tools for active imaging research. At the same time, small molecules are also very convenient for dose-related research information.
Small molecules are powerful and can precisely control the time or space of individual proteins or processes to control biological phenotypes. Small molecules have promoted our understanding of the biological pathways that affect the fate of stem cells, and are further used to regulate the renewal, survival, and direct reprogramming and differentiation of pluripotent stem cells. Small molecules also help identify signaling molecules, which define and maintain complex intracellular communication networks, controlling growth, differentiation, metabolism, and other key cellular functions.
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