New definition of bioprinting technology in medical field

Have you ever thought that one day your life will be linked to printing technology? After the printer finishes working, a skull, a blood vessel, and even a complete human organ will appear. This is not a horror movie, but a real medical technology.

3D printing technology in the medical field-artificial bones

The details of the world's first artificial mandible transplant surgery made by 3D printing technology have been announced. The transplant operation was performed in the Netherlands in June last year. The patient who received the transplant was an 83-year-old woman with osteomyelitis. Her postoperative recovery was in good condition, and the new mandible did not affect her language expression and ability to eat.

This new artificial bone 3D printing technology was jointly developed by the Belgian company LayerWise and researchers at the University of Hasselt, Belgium, and the organ production process is called "superimposed production method (AM)". Through this method, technicians can design the renderings of bone parts according to the specific needs of transplant patients, and then use high-precision laser q iang to melt titanium powder and spray them layer by layer to form a three-dimensional Finished artificial bone parts. The whole process does not require any glue or adhesive.

3D printing technology in the medical field-blood vessels

A team of scientists from the Fraunhofer Institute successfully developed artificial blood vessels using 3D printers and "multiphoton polymerization" technology. The resulting blood vessel has a flexible and strong structure that can be fused with the body's own tissue. At the same time, because its outer membrane is covered with modified biomolecules, it will not be rejected by the human body. If it can be put into medical applications, the technology will successfully solve the problem of shortage of artificial organs, which is very valuable for patients who want to perform organ transplantation.

3D printer can copy human bones

3D imaging of damaged bones, inkjet printing of imaging materials with a 3D printer, and injection of osteoblasts, can finally cultivate human bones accurately.

First, you need to 3D image the bones that need to be copied. If this bone is lost or severely damaged, you can mirror 3D image the "twin bone tissue" on the body. For example, if the patient's left thumb is severed and lost, then the right thumb can be imaged in 3D. The obtained 3D imaging is input to a 3D inkjet printer, which prints a thin layer of pre-selected materials, and then layer by layer until a 3D object is formed.

Scientists loaded tricalcium phosphate and a polylactic acid in the printer, which is the most basic element in the human body. This printed skeleton "scaffolding" contains thousands of micropores, and bone cells can be placed in it to gradually grow and grow, and eventually this "scaffolding" can biodegrade and disappear. The research team extracted CD117 cells from human bone marrow, which can develop into a kind of primary bone cells called "osteogenesis cells". The research team injected a gel into the "scaffold" of bones formed by 3D printers, which can cultivate Of primary bone cells provide nutritional development. After 15 weeks, the bone “scaffolding” eventually broke down under the skin on the back of the mouse, and the osteoblasts in the scaffolding formed the human skeleton.

After this technology called bioprinting matures, we will look like we have our own exclusive human organ bank and can print body organs that are only suitable for ourselves at any time; perhaps only 20 years, our organs can become Replaceable equipment, so that death due to organ aging may be avoided, and healthy bodies will exist for as long as sound thinking.

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